Diseases such as Alzheimer's disease, Huntington's disease, cystic fibrosis, BSE (Mad Cow disease), an inherited form of emphysema, and even many cancers are believed to result from protein misfolding.
It runs when your computer is on (connected to the net) and isn't being used. When you jump on it to do something it basically goes idle while you are using it, then it goes back to work when the computer becomes idle again. If your computer is on most of the time anyway, why not have it do something useful that someday could save lives and make the world a better place?
http://folding.stanford.edu/
http://folding.stanford.edu/download.html
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